Cheap Flights from Panama City to Medellin

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Flight deals from Panama City to Medellin

Looking for a cheap last-minute deal or the best return flight from Panama City to Medellin? Find the lowest prices on one-way and return tickets right here.

Medellin.$236 per passenger.Departing Wed, 16 Apr, returning Tue, 22 Apr.Return flight with Wingo.Outbound direct flight with Wingo departs from Balboa on Wed, 16 Apr, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Wingo departs from Medellin Jose Maria Cordova on Tue, 22 Apr, arriving in Balboa.Price includes taxes and charges.From $236, select.

Medellin.$250 per passenger.Departing Mon, 21 Apr, returning Thu, 5 Jun.Return flight with Wingo.Outbound direct flight with Wingo departs from Balboa on Mon, 21 Apr, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Wingo departs from Medellin Jose Maria Cordova on Thu, 5 Jun, arriving in Balboa.Price includes taxes and charges.From $250, select.

Medellin.$358 per passenger.Departing Sun, 15 Jun, returning Sun, 22 Jun.Return flight with Wingo.Outbound direct flight with Wingo departs from Balboa on Sun, 15 Jun, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Wingo departs from Medellin Jose Maria Cordova on Sun, 22 Jun, arriving in Balboa.Price includes taxes and charges.From $358, select.

Medellin.$364 per passenger.Departing Tue, 6 May, returning Sat, 10 May.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Tue, 6 May, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Copa departs from Medellin Jose Maria Cordova on Sat, 10 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $364, select.

Medellin.$390 per passenger.Departing Wed, 28 May, returning Sun, 1 Jun.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Wed, 28 May, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Copa departs from Medellin Jose Maria Cordova on Sun, 1 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $390, select.

Medellin.$390 per passenger.Departing Sun, 6 Jul, returning Fri, 11 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 6 Jul, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Copa departs from Medellin Jose Maria Cordova on Fri, 11 Jul, arriving in Panama City Tocumen International.Price includes taxes and charges.From $390, select.

Medellin.$390 per passenger.Departing Sun, 27 Apr, returning Sun, 4 May.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Sun, 27 Apr, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Copa departs from Medellin Jose Maria Cordova on Sun, 4 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $390, select.

Medellin.$407 per passenger.Departing Wed, 23 Jul, returning Fri, 1 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Panama City Tocumen International on Wed, 23 Jul, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Copa departs from Medellin Jose Maria Cordova on Fri, 1 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $407, select.

Find the cheapest month to fly from Panama City to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Medellin flights are currently cheapest in April.

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Direct flights from Panama City to Medellin

Alternative Panama City to Medellin routes

Looking for the cheapest, fastest or easiest route from Panama City to Medellin? You could fly into the following airports instead.

Panama City to Medellin: Flight information

The things to know before you go.

Cheapest flight found	$245
Cheapest month to fly	April
Average flight time	1 hr, 21 mins
Most popular airline	Copa
Average flights per week	143

Finding cheap flights from Panama City to Medellin: Frequently asked questions

How many airports are there in Medellin?

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.

How much are return flights from Panama City to Medellin?

The best price we found for a return flight from Panama City to Medellin is $245. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Panama City to Medellin?

1 hour and 21 minutes is the average flight time from Panama City to Medellin.

Which airlines fly direct from Panama City to Medellin?

Copa, United and Avianca El Salvador fly direct from Panama City to Medellin.

How many flights are there a week from Panama City to Medellin?

As of April 2025, there are 143 flights per week flying from Panama City to Medellin.

When is the cheapest time to fly from Panama City to Medellin?

The cheapest month to fly from Panama City to Medellin is usually April 2025.

Which is the cheapest airport to fly into in Medellin?

If you're flying from Panama City, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 18.9 km away from the centre of Medellin. We've found flights into this airport from $245.

Which upcoming date is cheapest to fly from Panama City to Medellin on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Medellin on Wednesday, 16 April 2025.

Can I get a direct flight from Panama City to Medellin?

Yes – the average flight time is 1 hour and 21 minutes.

How can I get the best flight deal from Panama City to Medellin?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Medellin?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Medellin?

In April, the average temperature is usually around 18°C. May is typically the warmest month in Medellin, when it usually averages around 21°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 15°C. The rainiest month is May.

Which is the cheapest airline to fly from Panama City to Medellin with?

The cheapest airline that flies to Medellin is Wingo .

Flying from Panama City to Medellin: what you need to know

There are a couple of main airports you can fly out of in Panama City. Check out your options departing from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB) when organising your flight from Panama City to Medellin.
Come in for landing at Jose Maria Cordova International Airport (MDE), the primary gateway of Medellin.
Expect to be travelling for 1 hour 25 minutes. On average, that's the time it takes for a direct flight from Panama City to Medellin. These two cities have the same timezone — UTC-5.
With 56 flights a week between the two airports, Tocumen International Airport (PTY) to Jose Maria Cordova International Airport (MDE) is the most popular route. Hop on the first flight from Panama City to Medellin with Copa Airlines at 07:01. If you're keen to make the most of your day before you fly, the last flight from PTY to MDE is with Copa Airlines at 21:27.
To ensure you get on your flight from Panama City to Medellin, leave enough time to check in and find your gate. Turning up two hours ahead of international departures and one hour before domestic flights is the general rule.
During popular months like June, it's best to get to the airport earlier. Arrive two hours before domestic departures and four hours ahead of an international flight when you fly during high season in general.
You can visit Colombia for tourism purposes without a visa if you have a passport from Panama. But before organising your cheap flight from Panama City to Medellin, double-check for the newest rules and regulations. Visa rules are subject to change, and you may need some documentation if your trip is for work or another reason.

Flying from Panama City

Tocumen International Airport (PTY)

You can reserve a direct flight from Panama City to Medellin departing from Tocumen International Airport (PTY). Begin your journey at PTY and touch down at Jose Maria Cordova International Airport (MDE).
Book your direct flight from Panama City to Medellin with Copa Airlines. This top airline operates departures from PTY.
We make it simple to book a flight from Panama City to Medellin with a stopover. To see your options departing from Tocumen International Airport, uncheck 'Direct flights only.' Then, choose a flight that has a stop long enough to see the sights of your chosen city. Some popular stopovers include:
- El Eden Airport (AXM)
- Alfonso B. Aragon Airport (CLO)
- El Dorado International Airport (BOG)
PTY is around 21 kilometres from central Panama City. If you're catching a cab, driving or ride-sharing from the centre, it'll take 21 minutes or so to get there, depending on traffic conditions. If you're using public transport, expect the trip time to be around 1 hour and 5 minutes.
Catching an early flight from Panama City to Medellin? Avoid rushing to the airport (and catch some extra z's) by choosing one of these stays close to Tocumen International Airport:

Panama Pacifico Airport (BLB)

It's also possible to take a direct flight from Panama City to Medellin departing Panama Pacifico Airport (BLB). Services from BLB will take you straight to Jose Maria Cordova International Airport (MDE).
You can board a direct flight from Panama City to Medellin with Wingo. This is one of the top airlines flying this route out of BLB.
Break up your flight from Panama City to Medellin with a stop so you can freshen up or tick another place off your list. Some popular stopovers between Tocumen International Airport and Medellin include:
- El Eden Airport (AXM)
- Alfonso B. Aragon Airport (CLO)
- El Dorado International Airport (BOG)
Depending on road traffic, you can drive to BLB from Panama City's centre in around 22 minutes. The airport is approximately 16 kilometres away.
Want to enjoy an extra night away before boarding your flight from Panama City to Medellin? Relax in a hotel near Panama Pacifico Airport before your holiday officially begins. Consider one of these stays:

Arriving in Medellin

Jose Maria Cordova International Airport (MDE)

Jose Maria Cordova International Airport (MDE) is around 24 kilometres from the centre of Medellin. With a car rental or if you're catching a cab, the drive is about 36 minutes.
Consider staying in a hotel close to MDE if you're catching a late flight from Panama City to Medellin. Choose one of these options and skip the long transfer:

Enrique Olaya Herrera Airport (EOH)

Enrique Olaya Herrera Airport (EOH) is around 6 kilometres from the centre of Medellin. After your flight from Panama City to Medellin, allow for a drive time of approximately 16 minutes to reach the heart of the city.
Public transport will get you there in approximately 31 minutes.
Hang up the 'Do not disturb' sign and relax at a hotel close to EOH. Here are a few options where you can settle in after your flight from Panama City to Medellin:

How to find the cheapest flights from Panama City to Medellin

$117 is currently the lowest price for a one-way ticket from Panama City to Medellin. A return flight starts at $236. These fares can change based on demand.
Lock in cheap tickets from Panama City to Medellin by booking 11 months ahead. Based on our research, that's the sweet spot for finding the biggest deals.
Schedule your trip for July. That's the cheapest month for flight tickets from Panama City to Medellin. If you're flexible with your travel dates, use the 'Whole month' tool to see the cheapest price across every month.
Create a Price Alert for cheap tickets from Panama City to Medellin. You don't need to check every day to find out if prices have dropped. We'll notify you as soon as the price changes.
Use filters to tailor your flights from Panama City to Medellin. Select your ideal departure and arrival times, airlines and number of stops. Alternatively, sort your results by 'Cheapest' to find the best deals.

Best time to go to Medellin

It's time to work out your dates for your flight from Panama City to Medellin. August is the most popular month to travel to Medellin. If you like a more low-key vibe, go in April.
Lock in your flight from Panama City to Medellin for August if you want to visit the city during its warmest month. Expect temperatures in Medellin to range from 11ºC to 27ºC.
Search for cheap tickets from Panama City to Medellin in July if you like travelling in cooler conditions. Temperatures are at their lowest around then, ranging between 11ºC and 27ºC on average.

More about Medellin

When it comes to searching for somewhere to rest your head, you'll find the most popular stays in Medellin right here. Browse these options after locking in your flight from Panama City to Medellin:
All great adventures should include some sightseeing. Parque Arvi, Comuna 13 and Botero Plaza are attractions you won't want to skip in Medellin.

Complete your Medellin trip with a car rental

Finding you a cheap flight from Panama City to Medellin isn't our only party trick. Check out our car rentals in Medellin and explore the city on your own terms. We find deals from trusted car rental companies and put them all in one place. You can instantly compare offers and then book with no fees.