Skyscanner

Cheap Flights from Panama City to Sao Paulo

Travellers and cabin class

Compare Panama City Tocumen International to Sao Paulo Guarulhos flight deals

Find the cheapest month or even day of the year to fly to Sao Paulo Guarulhos

Book the best Sao Paulo Guarulhos fare with no extra fees

Flight deals from Panama City Tocumen International to Sao Paulo Guarulhos

Looking for a cheap last-minute deal or the best return flight from Panama City Tocumen International to Sao Paulo Guarulhos? Find the lowest prices on one-way and return tickets right here.
Sao Paulo.$566 per passenger.Departing Sun, 11 May, returning Tue, 13 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 11 May, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Tue, 13 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $566, select.
Sao Paulo.$568 per passenger.Departing Mon, 28 Apr, returning Mon, 5 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 28 Apr, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Mon, 5 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From $568, select.
Sao Paulo.$623 per passenger.Departing Sun, 8 Jun, returning Sun, 15 Jun.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 8 Jun, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Sun, 15 Jun, arriving in Panama City Tocumen International.Price includes taxes and charges.From $623, select.
Sao Paulo.$625 per passenger.Departing Tue, 30 Sep, returning Tue, 7 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 30 Sep, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Tue, 7 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $625, select.
Sao Paulo.$625 per passenger.Departing Mon, 6 Oct, returning Thu, 30 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 6 Oct, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Thu, 30 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From $625, select.
Sao Paulo.$625 per passenger.Departing Mon, 4 Aug, returning Mon, 11 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 4 Aug, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Mon, 11 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $625, select.
Sao Paulo.$626 per passenger.Departing Sun, 21 Sep, returning Sat, 27 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 21 Sep, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Sat, 27 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From $626, select.
Sao Paulo.$626 per passenger.Departing Fri, 11 Jul, returning Tue, 5 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 11 Jul, arriving in Sao Paulo Guarulhos.Inbound indirect flight with Avianca, departs from Sao Paulo Guarulhos on Tue, 5 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From $626, select.

Find the cheapest month to fly from Panama City Tocumen International to Sao Paulo Guarulhos

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City Tocumen International to Sao Paulo Guarulhos flights are currently cheapest in May.
Apr
Find prices
May
from $566
Jun
from $623
Jul
from $627
Aug
from $625
Sep
from $626
Oct
from $625
Nov
from $747
Dec
Find prices
Jan
Find prices
Feb
Find prices
Mar
from $630

Direct flights from Panama City Tocumen International to Sao Paulo Guarulhos

Panama City Tocumen International to Sao Paulo Guarulhos: Alternative routes

Compare routes from Panama City Tocumen International to Sao Paulo below. You may find an airport to fly into that's cheaper, faster, or easier than Sao Paulo Guarulhos.

Panama City to Sao Paulo: Flight information

The things to know before you go.
Cheapest flight found$566
Cheapest month to flyMay
Average flight time6 hrs, 43 mins
Most popular airlineCopa
Average flights per week118

Finding cheap flights from Panama City Tocumen International to Sao Paulo Guarulhos: Frequently asked questions

The best price we found for a return flight from Panama City Tocumen International to Sao Paulo Guarulhos is $566. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 43 minutes is the average flight time from Panama City Tocumen International to Sao Paulo Guarulhos.
Copa, GOL Linhas Aéreas and Azul Airlines fly direct from Panama City Tocumen International to Sao Paulo Guarulhos.
As of April 2025, there are 118 flights per week flying from Panama City Tocumen International to Sao Paulo Guarulhos.
The cheapest month to fly from Panama City Tocumen International to Sao Paulo Guarulhos is usually April 2025.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Panama City Tocumen International Airport to Sao Paulo Guarulhos Airport on Sunday, 11 May 2025.
Yes – the average flight time is 6 hours and 43 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Paulo Guarulhos but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Paulo is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Avianca and Copa offer the cheapest flight tickets to Sao Paulo Guarulhos.

Flying from Tocumen International Airport (PTY) to Sao Paulo-Guarulhos International Airport (GRU): what you need to know

  • The average time for a direct flight from Tocumen International Airport to Sao Paulo-Guarulhos International Airport is 7 hours.

  • Sao Paulo's timezone is UTC-3, which makes Sao Paulo two hours ahead of Panama City.

  • Take your pick of 40 weekly Tocumen International Airport to Sao Paulo-Guarulhos International Airport flights. The 11:50 departure with Copa Airlines is the earliest you can take. Copa Airlines operates the latest service of the day at 21:42.

  • To ensure you catch your PTY to GRU flight, leave enough time to check in and find your gate. Turning up two hours before international departures and an hour before domestic flights is the general rule.

  • During popular months such as June, you'll want to get to the airport even earlier. Arrive two hours before domestic departures and four hours ahead of international flights whenever you're travelling during a high season in general.

  • Getting to Sao Paulo (and then discovering more of Brazil!) is a cinch with Copa Airlines. This popular carrier has direct flights from Tocumen International Airport to Sao Paulo-Guarulhos International Airport.

  • Copa Airlines has the highest passenger demand on this route.

  • The most punctual carrier that operates PTY to GRU flights is Copa Airlines. Its services arrive without delay 71.17% of the time.

  • We make it a piece of cake to book a flight with a stopover. To see all your options for tickets from Tocumen International Airport to Sao Paulo-Guarulhos International Airport, uncheck 'Direct flights only.' Then, pick a flight offering a stop long enough to explore your chosen city. Top stopovers between PTY and GRU include:

    • El Dorado International Airport

    • Jorge Chavez International Airport

    • Ministro Pistarini Airport

How to find the cheapest flights from Tocumen International Airport (PTY) to Sao Paulo-Guarulhos International Airport (GRU)

  • Currently, $363 is the lowest price we've seen for a one-way Tocumen International Airport to Sao Paulo-Guarulhos International Airport flight. The best price for a return ticket is $566. Bear in mind that fares could change due to demand at the time of booking.

  • Book three months before you travel. After crunching the numbers on our calendar, this is how far you'll want to book ahead to secure cheap tickets from PTY to GRU.

  • The cheapest month for flights from Tocumen International Airport to Sao Paulo-Guarulhos International Airport is February. Use the 'Whole month' tool to find the lowest airfares if you have flexible dates.

  • Cut down on the time spent looking for cheap flights from PTY to GRU by setting up a Price Alert. You'll get an email or notification through the app when a lower fare pops up.

  • Choose your ideal arrival and departure times, airlines and number of stops with the filters. Or sort your results by 'Cheapest' to get the best deals on flights from Tocumen International Airport to Sao Paulo-Guarulhos International Airport.

Handy information about Tocumen International Airport (PTY)

  • 86.03% of flights departing from Tocumen International Airport reach their destination according to schedule. Given its dependable on-time performance, you're unlikely to experience delays when taking off from PTY.

  • Central Panama City to Tocumen International Airport is around 21 kilometres. Depending on traffic, it'll take you about 20 minutes to get there if you're catching a cab, ride-sharing or driving.

  • Expect a trip time of about 1 hour 5 minutes when using public transport.

  • Need a convenient hotel close to PTY? If you're catching an early flight from Tocumen International Airport to Sao Paulo-Guarulhos International Airport, these stays will have you moments from your departure lounge:

Arriving at Sao Paulo-Guarulhos International Airport (GRU)

Getting from Sao Paulo-Guarulhos International Airport (GRU) to central Sao Paulo

  • Sao Paulo-Guarulhos International Airport is roughly 26 kilometres from the centre of Sao Paulo. The drive time takes around 30 minutes.

  • It'll take around 1 hour 20 minutes to get there using public transport.

When to fly to Sao Paulo-Guarulhos International Airport (GRU)

  • It's time to choose your dates for your flight from Tocumen International Airport to Sao Paulo-Guarulhos International Airport. July is the busiest month to visit Sao Paulo. If you prefer a quieter vibe, go in April.

  • The warmest month in Sao Paulo is February, with the temperature ranging between 18ºC (64ºF) and 28ºC (82ºF). Lock in your flights from Tocumen International Airport to Sao Paulo-Guarulhos International Airport in this month if this is the type of weather you enjoy.

  • Look for cheap tickets from PTY to GRU in July if you like cooler conditions. Temperatures are at their lowest then, ranging between 12ºC (54ºF) and 25ºC (77ºF) on average.

Explore more of Brazil

  • You've seen Sao Paulo, now it's time to discover other parts of Brazil. Travel about 499 kilometres north-east to Belo Horizonte to check off its top attractions. From Abilio Barreto Historical Museum to Matiz Arte Objeto and Deck Vertedouro, you'll have a packed itinerary ahead.

  • Curitiba is another must-experience destination in Brazil and is around 338 kilometres south-west of Sao Paulo. No journey is complete without experiencing Jardim Botanico de Curitiba, Museu Oscar Niemeyer and Largo da Ordem.

Plan the rest of your trip from Panama City to Sao Paulo

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.