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Cheap Flights from Manaus to Panama City

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Compare Manaus to Panama City flight deals

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Flight deals from Manaus to Panama City

Looking for a cheap last-minute deal or the best return flight from Manaus to Panama City? Find the lowest prices on one-way and return tickets right here.
Panama City.$416 per passenger.Departing Tue, 14 Oct, returning Sat, 18 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Tue, 14 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 18 Oct, arriving in Manaus.Price includes taxes and charges.From $416, select.
Panama City.$417 per passenger.Departing Thu, 10 Jul, returning Wed, 16 Jul.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Thu, 10 Jul, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Wed, 16 Jul, arriving in Manaus.Price includes taxes and charges.From $417, select.
Panama City.$417 per passenger.Departing Wed, 24 Sep, returning Fri, 3 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Wed, 24 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 3 Oct, arriving in Manaus.Price includes taxes and charges.From $417, select.
Panama City.$418 per passenger.Departing Sun, 17 Aug, returning Mon, 25 Aug.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Sun, 17 Aug, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 25 Aug, arriving in Manaus.Price includes taxes and charges.From $418, select.
Panama City.$418 per passenger.Departing Wed, 27 Aug, returning Tue, 9 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Wed, 27 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 9 Sep, arriving in Manaus.Price includes taxes and charges.From $418, select.
Panama City.$418 per passenger.Departing Fri, 2 May, returning Thu, 8 May.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Fri, 2 May, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Thu, 8 May, arriving in Manaus.Price includes taxes and charges.From $418, select.
Panama City.$418 per passenger.Departing Tue, 14 Oct, returning Sat, 18 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Manaus on Tue, 14 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sat, 18 Oct, arriving in Manaus.Price includes taxes and charges.From $418, select.
Panama City.$422 per passenger.Departing Wed, 30 Apr, returning Sat, 3 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Manaus on Wed, 30 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 3 May, arriving in Manaus.Price includes taxes and charges.From $422, select.

Find the cheapest month to fly from Manaus to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Manaus to Panama City flights are currently cheapest in October.
Apr
Find prices
May
from $418
Jun
from $423
Jul
from $418
Aug
from $418
Sep
from $423
Oct
from $417
Nov
from $668
Dec
from $426
Jan
from $1,042
Feb
from $668
Mar
from $669

Direct flights from Manaus to Panama City

Alternative Manaus to Panama City routes

Looking for the cheapest, fastest or easiest route from Manaus to Panama City? You could fly into the following airports instead.

Manaus to Panama City: Flight information

The things to know before you go.
Cheapest flight found$417
Cheapest month to flyOctober
Average flight time3 hrs, 48 mins
Most popular airlineAzul Airlines
Average flights per week25

Finding cheap flights from Manaus to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Manaus to Panama City is $417. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
3 hours and 48 minutes is the average flight time from Manaus to Panama City.
Azul Airlines, Copa and United fly direct from Manaus to Panama City.
As of April 2025, there are 26 flights per week flying from Manaus to Panama City.
The cheapest month to fly from Manaus to Panama City is usually April 2025.
If you're flying from Manaus Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from $417.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Manaus Airport to Panama City on Tuesday, 14 October 2025.
Yes – the average flight time is 3 hours and 48 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In April, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Avianca and Copa offer the cheapest flight tickets to Panama City.

Travelling from Eduardo Gomes International Airport (MAO) to Panama City: what you need to know

  • Take a direct flight from Eduardo Gomes International Airport to Panama City and you'll be in the air for an average of 4 hours.

  • The timezone in Panama City is UTC-5. The city is 1 hour behind Manaus, where Eduardo Gomes International Airport is located.

  • With 8 flights a week between the two airports, Eduardo Gomes International Airport (MAO) to Tocumen International Airport (PTY) is the busiest route. Copa operates the earliest flight at 03:35. If you'd like to get more out of your day before flying, the latest flight from MAO to PTY is with Copa at 03:45.

  • For a smooth journey, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This will give you plenty of time to board your flight from MAO to Panama City.

  • Travelling during a peak time such as June? School holidays and other popular periods can mean longer queues and delays at security. Play it safe and arrive up to four hours ahead of an international flight and two hours before a domestic departure.

  • You can get a direct flight from Eduardo Gomes International Airport to Panama City. Start your trip at MAO and end it at Tocumen International Airport (PTY).

  • Copa is a well-known airline that offers direct flights from Eduardo Gomes International Airport to Panama City.

  • Whether you'd like to discover another city as part of your journey or just take a break, we make it a cinch to find a flight with a stopover. To check out your options, uncheck 'Direct flights only.' El Dorado International Airport (BOG) is a stop you can make during your flight from MAO to Panama City.

  • If you hold a passport from Brazil and are travelling to Panama for tourism purposes, you won't need a visa. However, entry and visa requirements may differ based on your reason for visiting and are subject to change. For the most up-to-date information, check with your destination's nearest consulate or embassy before booking a cheap ticket from Eduardo Gomes International Airport to Panama City.

  • The journey from central Manaus to MAO takes around 48 minutes on public transport. If you ride-share, drive or get a cab, you'll cover the 13 kilometres in 19 minutes or so, depending on traffic conditions.

  • After a relaxed start to your journey? Stay near MAO. Whether you're catching an early flight from Eduardo Gomes International Airport to Panama City or want to avoid feeling rushed, these hotels are perfect:

How to find the cheapest flights from Eduardo Gomes International Airport (MAO) to Panama City

  • The best price we've found for a one-way ticket from Eduardo Gomes International Airport to Panama City is $180. The cheapest price for a return flight is $417. Bear in mind fares can change due to availability at the time of booking.

  • Don't leave things to the last moment. You're more likely to get cheap tickets from MAO to Panama City if you book ahead. Airlines often offer some amazing early bird deals.

  • Getting cheap tickets from Eduardo Gomes International Airport to Panama City is easier if you're flexible with your travel dates. Try using the 'Whole month' function to show the best prices throughout the month and snap up a great deal.

  • Locking in a cheap ticket from MAO to Panama City is easy with Price Alerts. All you need to do is create one of these automatic alerts and we'll get in touch as soon as the price has fallen.

  • Tailor your travel plans with filters. Choose your ideal departure and arrival times, airlines and total journey duration. You can also sort the results by 'Best,' 'Fastest' or 'Cheapest' flights from Eduardo Gomes International Airport to Panama City.

Airports in Panama City

Tocumen International Airport (PTY)

Marcos A. Gelabert International Airport (PAC)

Best time to go to Panama City

  • June is the busiest month to hop on a flight from Eduardo Gomes International Airport to Panama City while February is the quietest. To work out the ideal time to visit Panama City, consider whether you prefer a lively vibe or a quieter pace.

  • Book your flight from Eduardo Gomes International Airport to Panama City for March to visit the city during its warmest month. Expect temperatures to range from 21ºC to 32ºC.

  • For cooler conditions, look for a cheap flight from MAO to Panama City in February when temperatures average between 22ºC and 31ºC.

More about Panama City

  • When it comes to searching for somewhere to rest your head, you'll find the most popular stays in Panama City right here. Browse these hotels after you've booked your flight from Eduardo Gomes International Airport to Panama City:

  • Panama Canal Museum and Casco Viejo are just the start of the big attractions to put on your Panama City to-do list. Keep the adventure rolling by checking out Cinta Costera.

Complete your Panama City trip with a car rental

  • We use the same magic that helped you find your cheap flight from Eduardo Gomes International Airport to Panama City to track down amazing deals on car rentals. Search for your ride in seconds and easily compare your options. Plus you'll find all the info on car rentals in Panama City, from the most popular car type to the best time to book.

Plan the rest of your trip from Manaus to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.